SpinΩ is a miniaturized, motorized, and modular system that is compatible with any standard multi-well tissue culture plates (12-well version shown). It provides a higher throughput platform to culture 3D tissues by reducing the amount of media required and promoting tissue survival. SpinΩ has proven to support the culture of human brain organoids and to be cost-effective for drug efficacy/toxicity testing. The technology was first conceptualized and developed at Johns Hopkins Institute for Cell Engineering by several talented high school student interns. 3Dnamics is further refining the bioreactor and continually inventing new tools to advance stem cell research.